Q.P. Code: 201001 Reg. no.: …………………
Second Professional MBBS Degree Supplementary Examinations, September 2015
Pharmacology- Paper I
Time: 2 Hours Total
Marks: 40
• Answer all questions
• Draw diagrams wherever
necessary
Essays: (2x6=12)
1.
Enumerate four groups of drugs used in the treatment of
Parkinson’s disease. Describe the pharmacological actions and adverse effects
of levodopa. What is the advantage of combining levodopa
with the peripheral decarboxylase
inhibitor. (2+3+1= 6)
2.
Read the clinical problem and answer the following
questions: 30 years old man was admitted
in emergency ward with acute abdominal pain. After diagnosed with acute
appendicitis, he was taken for surgery. On the operation table, after
administration of a skeletal muscle relaxant, patient developed difficulty in
breathing and went in for apnoea.
• Which
skeletal muscle relaxant is responsible for this reaction.
• What
is the reason for the apnoea.
|
•
How will you manage the patient.
|
(1+3+2=6)
|
|
Short notes:
3. Trans
dermal therapeutic system
4. Amphetamine
5. Second
generation antihistamines
6. Tramadol
7.
Ramipril
|
(5x3=15)
|
|
Answer briefly:
8. Rationale
for use of calcium channel blockers in angina
9. Rationale
for use of ethanol in methanol poisoning
10. Rationale
for use of prostaglandin in acid peptic disease
11. Rationale
for use of physostigmine in atropine poisoning
12. Pharmacovigilance
|
(5x1=5)
|
|
Name two drugs:
|
(8x1=8)
|
13. Cholinesterase
reactivators
14. Intravenous
general anesthetics
15. Inhalational
steroids
16. Centrally
acting muscle relaxants
17. Nasal
decongestants
18. Pure
opioid antagonists
19. Low
molecular weight heparins
20. Cardio
selective beta blockers
