QP Code: 201001 Reg.
no.: …………………
Second Professional MBBS Degree Examinations, April 2013
Pharmacology- Paper I
Time: 3 Hours Total Marks: 40
• Answer all questions
• Draw diagrams wherever
necessary
Essays: (2x6=12)
1. A 24year old man is brought to the hospital with complaints of unconsciousness , sustained contractions (tonic) of all the body muscles followed by periods of muscle contraction alternating with periods of relaxations(clonic) lasting 1 to 2 minutes . Answer the following:
•
What are the drugs that can be prescribed to this
patient.
•
Describe the pharmacokinetics and adverse effects of
any one such drug.
2.
Classify diuretic agents. Describe the mechanism of
action, uses and adverse effects of furosemide. (2+2+1+1=6)
3.
Calcium channel blockers
4.
Drug treatment of anti cholinesterase poisoning
5.
Kinetics of elimination
6.
Halothane
7.
Nicorandil
Answer briefly: (5x1=5)
8.
Rationale of combining beta blockers with long acting
nitrates
9.
Clinical uses of prostaglandins
10.
Mechanism of action of disulfiram
11.
Flumazenil
12.
Hofmann elimination
Name two drugs for: (8x1=8)
13. Drugs used in Myasthenia
gravis
14. Uterine
relaxants
15. Mast
cell stabilizers
16. Mucolytics
17. Low
molecular weight heparins
18. Anti
platelet drugs
19. Drug
induced parkinsonism
20. 5HT
antagonists