Saturday 8 August 2015

BIOCHEMISTRY - AIPGMEE 2011 QUESTIONS AND ANSWERS

1. Thiamine deficiency causes decreased energy production because?
A.it is required for the process of transamination
B.it is co-factor in oxidative reduction
C.it is co-enzyme for transketolase in pentose phosphate pathway
D.it is co-enzyme for pyruvate dehydrogenase & alpha ketoglutarate dehydrogenase

Ans. D.it is co-enzyme for pyruvate dehydrogenase & alpha ketoglutarate dehydrogenase
2.What factor is responsible for deciding whether an antibody will remain membrane bound or get secreted?
A. Carbohydrate content
B. Class switching
C. Differential RNA splicing
D. Surface charge

Ans. C. Differential RNA splicing
3.Vitamin K is involved in the post translational modification of?
A. Glutamate
B. Aspartate
C. Tyrosine
D. Tryptophan

Ans. Glutamate
4.Which among the following is not a cause of fasting hypoglycemia?
A. Glucagon excess
B. Glucose 6 phospatase deficiency
C. Cirrhotic liver damage
D. Glycogen synthase deficiency


Ans. A. Glucagon excess
5.Cell fusion is a innovative method of preparing specific antibodies.Technique to induce cell fusion includes following all except?
A. Attaching inactive viral particle on cell membrane
B. Adding ethylene glycol
C. Applying a small electric current
D. Reducing the viscosity of the membrane

Ans.D. Reducing the viscosity of the membrane
6.Urea cycle occurs in:
A. Liver
B. Intestine
C. Brain
D. Kidney

Ans. A. Liver
7.Which of the following change in a vector used to increase the yield of protein produced in recombinant protein synthesis?
A. Inducible promoter
B. Genes for protease inhibitors
C. Translation initiation
D. Translation and transcription termination

Ans. A. Inducible promoter
8.Two plants are grown. One to express green fluorescent pigment & Other express Fire fly luciferase containing media. Which plant will glow in the dark?
A. Both plants will glow
B. Neither will glow
C. Plant expressing green fluorescent pigment will glow
D. Plant expressing firefly luciferrase will glow

Ans. D. Plant expressing firefly luciferrase will glow
9.A patient who was given primaquin develops hemolysis. The probable cause may be
A.Glucose 6 phosphate dehydrogenase deficiency
B.Glucose 6 phosphatase deficiency
C. Alpha keto glutarate dehydrogenase deficiency
D. Pyruvate Kinase Deficiency

Ans. A.Glucose 6 phosphate dehydrogenase deficiency
10. Transfer of an amino group from an amino acid to an alpha keto acid is done by?
A.Tranaminases
B.Aminases
C.Transketolase
D.Decarboxylase

Ans. A.Tranaminases
Q.11 Which of the following statements about high density lipoproteins (HDL) is false-
A.HDL increases oxidation of LDL
B.HDL reduces foam cell production by ldl
C.HDL is best predictor of CAD
D.HDL helps to clear lipids from atheroma

Ans. A.HDL increases oxidation of LDL