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Friday 7 August 2015

PHARMACOLOGY PAPER 1- 2015 FEBRUARY- 2ND MBBS KUHS

Q.P. Code: 201001                                                 Reg. no.: ................ ..
Second Professional MBBS Degree Examinations. February 2015

Pharmacology- Paper I

Time: 2 Hours                                           Total Marks:40

  • Answer all questions
  • Draw diagrams wherever necessary

Essays (2X6=12)

1. Enumerate four groups of non-steroidal anti-inflammatory drugs with the example each. Describe the   pharmacological actions, adverse effects and therapeutic uses of any one of them. (2+2+1+1=6)

2. Read the clinical problem and answer the following question: Mr.Shankar, 54 years suddenly developed severe chest pain. He was a diabetic and admitted in the ICCU with the diagnosis acute myocardial infarction,

  • List the drug to be started immediately after acute myocardial infarction.
  • Mention the mechanism of action and pharmacological action of fibrinolytics
  • Name the analgesics used to relieve pain and its rationale for the same (2+ 2+ 2=6)


Short notes: (5x3=15)

3. Atropine
4. Drug antagonism.
5. Halothane
6. Diazepam
7. Heparin.

Answer briefly: (5x1=5)
8. Two uses and two adverse effects of propranolol
9. Explain briefly why physostigmine is preferred over neostigmine for the treatment of glaucoma.
10. Rationale of using terazosin in benign prostatic hypertrophy
11. Mechanism of action of lignocaine.
12. Teratogenicity with one example.

Name two drugs: (8x1=8)

13. Angiotensin converting enzyme inhibitor
14. The treatment of migraine
15. Nasal decongestants
16. The treatment of cardiac failure
17. Ototoxic diuretics
18. Short acting agents for insomnia
19. Treatment of methanol poisoning
20. Opioid antagonist