Q224: The following statements regarding finasteride are true except ?
A) It is used in the medical treatment of benign prostatic
hypertrophy (BPH)
B) Impotence is well documented after its use
C) It blocks the conversion of dihydrotestosterone to
testosterone
D) It is a 5-á-reductase inhibitor
Answer: C) It blocks the conversion of dihydrotestosterone
to testosterone
Q225: Eternacept acts by one of the following
mechanisms ?
A) By blocking tumor necrosis factor
B) By blocking bradykinin synthesis
C) By inhibiting cyclo-oxygenase-2
D) By blocking lipoxygenase
Answer: A) By blocking tumor necrosis factor
Q226: All of the following are the disadvantages of
anesthetic ether, except ?
A) Induction is slow
B) Irritant nature of ether increases salivary and bronchial
secretions
C) Cautery can not be used
D) Affects blood pressure and is liable to produce
arrhythmias
Answer: D) Affects blood pressure and is liable to produce
arrhythmias
Q227: In unconjugated hyperbilirubinemia, the risk
of kernicterus increases with the use of ?
A) Ceftriaxone
B) Phenobarbitone
C) Ampicillin
D) Sulphonamide
Answer: D) Sulphonamide
Q228: All of the following are topically used
sulphonamides except ?
A) Sulphacetamide
B) Sulphadiazine
C) Silver sulphadiazine
D) Mafenide
Answer: B) Sulphadiazine
Q229: Oculogyric crisis is known to be produced by
all of the following drugs except ?
A) Trifluoperazine
B) Atropine
C) Perchlorperazine
D) Perphenazine
Answer: B) Atropine
Q230: Inverse agonist of benzodiazepine receptor is
?
A) Phenobarbitone
B) Flumazenil
C) Beta-carboline
D) Gabapentin
Answer: C) Beta-carboline
Q231: The group of antibiotics which possess
additional anti-inflammatory and immunomodulatory activities is ?
A) Tetracyclines
B) Polypeptide antibiotics
C) Fluoroquinolones
D) Macrolides
Answer: D) Macrolides
Q232: With which of the following theophylline has
an antagonistic interaction ?
A) Histamine receptors
B) Bradykinin receptors
C) Adenosine receptors
D) Imidazoline receptors
Answer: C) Adenosine receptors
Q233: One of the following is not penicillinase
susceptible ?
A) Amoxicillin
B) Penicillin G
C) Piperacillin
D) Cloxacillin
Answer: D) Cloxacillin
Q234: Which one of the following is best associated
with Lumefantrine ?
A) Antimycobacterial
B) Antifungal
C) Antimalarial
D) Antiamoebic
Answer: C) Antimalarial
Q235: Which one of the following drugs increases
gastro-intestinal motility ?
A) Glycopyrrolate
B) Atropine
C) Neostigmine
D) Fentanyl
Answer: C) Neostigmine
Q236: Which one of the following is the fastest
acting inhalational agent ?
A) Halothane
B) Isoflurane
C) Ether
D) Sevoflurane
Answer: D) Sevoflurane
Q237: Which one of the following drugs has been
shown to offer protection from gastric aspiration syndrome in a patient with
symptoms of reflux ?
A) Ondansetron
B) Metoclopramide
C) Sodium citrate
D) Atropine
Answer: B) Metoclopramide
Q238: A highly ionized drug ?
A) Is excreted mainly by the kidney
B) Can cross the placental barrier easily
C) Is well absorbed from the intestine
D) Accumulates in the cellular lipids
Answer: A) Is excreted mainly by the kidney
Q239: Nevirapine is a ?
A) Protease inhibitor
B) Nucleoside reverse transcriptase inhibitor
C) Non-nucleoside reverse transcriptase inhibitor
D) Fusion inhibitor
Answer: C) Non-nucleoside reverse transcriptase inhibitor
Q240: Which one of the following drugs is
'Topoisomerase I inhibitor' ?
A) Doxorubicin
B) Irinotecan
C) Etoposide
D) Vincristine
Answer: B) Irinotecan
Q241: The following drugs have significant drug
interaction with digoxin, except ?
A) Cholestyramine
B) Thiazide diuretics
C) Quinidine
D) Amlodipine
Answer: D) Amlodipine
Q242: One of the following is not true about
nesiritide ?
A) It is a brain natriuretic peptide analogue
B) is used in acutely decompensated heart failure
C) It has significant oral absorption
D) It has a short half-life
Answer: C) It has significant oral absorption
Q243: Dry mouth during antidepressant therapy is
caused by blockade of ?
A) Muscarinic acetyl choline receptors
B) Serotonergic receptors
C) Dopaminergic receptors
D) GABA receptors
Answer: A) Muscarinic acetyl choline receptors
Q244: All of the following are hallucinogens, except
?
A) LSD
B) Phencyclidine
C) Mescaline
D) Methylphenidate
Answer: D) Methylphenidate
Q245: The major difference between typical and
atypical antipsychotics is that ?
A) The latter cause minimal or no increase in prolactin
B) The former cause tardive dyskinesia
C) The former are available as parenteral preparations
D) The latter cause substantial sedation
Answer: B) The former cause tardive dyskinesia
