First Professional MBBS Degree Examinations, August 2012
BIOCHEMISTRY PAPER 1
Time: 3 Hours Total Marks:50
- Answer all questions
- Draw diagrams wherever necessary
Essay (10)
1.Mention the reactions by which glycine is synthesized and
catabolized. Add a note on the specialized products formed and mention the
disorders associated with glycine metabolism (2+6+2=10)
Short essays (2×5=10)
2. Fatty acid synthase complex
3. Describe the reactions of urea cycle. Discuss the
interrelationship between urea cycle and citric acid cycle
Short notes (5×3=15)
4. Mention three examples of trans methylation reactions
5. Ketosis
6. Secondary structure of proteins
7. Importance of glutamine
8. Covalent modification
Answer briefly (5×2=10)
9. Hartnup’s disease
10. Classification of glycolipids
11. Uncouplers of oxidative phosphorylation
12. Functions of cholesterol
13. Significance of HMP shunt
Give precise answers (5×1=5)
14. Enzyme defect in maple syrup urine disease
15. Epimer of glucose
16. Normal level of serum albumin
17. Name the biochemical test for phenyl ketonuria
18. Important product of Rapaport Lubering cycle in RBC
