First Professional MBBS Degree Examination, August 2012
BIOCHEMISTRY PAPER 2
Time: 3 HRS Total
marks: 50
- Answer all questions
- Draw diagrams whenever necessary
Essay (10)
1. Describe the sources, RDA, biochemical functions and
deficiency manifestations of vitamin D
(2+1+5+2=10)
Short essays (2×5=10)
2. Describe the salvage pathway of purine nucleotide
synthesis with its significance. Describe the disorder associated with it.
3. Describe the structure and functions of tRNA
Short notes (5×3=15)
4. Define metabolic acidosis
5. Define replication and mention four inhibitors of
replication
6. Marasmus
7. Mention the functions of zinc
8. Cause and clinical features of acute intermittent porphyria
Answer briefly (5×2=10)
9. Define nucleotide. Define two adenosine nucleotide derivatives
10. Point mutation
11. Name the liver function tests
12. Functions of biotin
13. Define thalassemia and mention the different types of
thalassemia
Give precise answers
(5×1=5)
14. Name two tumour suppressor genes
15. Define genetic code
16. Name two hormones causing increased levels of cyclic AMP
17. Name the coenzyme required for transamination reactions
18. Mention the normal serum calcium level
