BIOCHEMISTRY PAPER 2-MODEL QN-KUHS-2011

                                                                                       

MODEL QUESTION PAPER

First Professional MBBS Degree Examination

Paper - II BIOCHEMISTRY

Time: 3 hrs                                                                                                   Max marks: 50

Instructions:

• Draw diagrams wherever necessary

• Answer all questions.

1. What is translation? Discuss the process of translation and add a

note on post translational modifications.                                                    (1+6+3=10 marks)

Discuss the following

2. Porphyrias.

3. Renal mechanism of regulation of blood pH                                          (2x5=10 marks)

Write short notes on:

4. Telomerase

5. Oroticaciduria.

6. Cytochrome P450.

7. Diseases related to copper metabolism

8. Role of one carbon compounds in purine & pyrimidine formation.         (5x3=15 marks)

Write briefly:

9. Creatinine clearance

10. Metabolic role of vitamin C.

11. Factors affecting electrophoresis.

12. Effects of radiation on normal tissue

13. Deficient enzyme and clinical features in Lesch – Nyhan

syndrome.                                                                                                      (5x2=10 marks)

Give precise answers:-

14. Nucleosomes

15. Klenow fragment

16. Name two selenium containing enzymes.

17. Mention any two oncosuppressor gene.

18. Name the most important extra cellular cation and write its normal

serum level.                                                                                                  (5x1=5 marks)