This section contains chapter wise arrangement of Previously asked questions in MBBS Degree Examinations conducted by KUHS(Kerala University of Health Sciences)
- Describe the intrinsic pathway of coagulation. Mention one test for assessing it
- Role of lymphocytes in immune functions/ Role of lymphocytes in immunity
- T lymphocyte
- Plasma cell
- Intrinsic mechanism of coagulation
- Formation and functions of Lymph
- Rh blood group system
- Bombay blood group
- Sickle cell anemia
- Fetal hemoglobin
- Hemophilia
- Maturation factors of RBC
Explain the Physiological basis
- Clotting of blood does not occur In-vivo normally
- Clotting occurs when blood is kept in a glass tube
- Purpura and hemophilia
- Idiopathic thrombocytopenic purpura
- Dicumarol as an anticoagulant
- Leucocytosis
- Reticulocytosis
- Rh incompatibility
- Megaloblasts in vitamin B12 deficiency anemia
- Bleeding tendency in vitamin k deficiency
- Protective effect of vaccination
Cases
1. A 40 years old obese women, complained of repeated
attacks of
righthypochondrial pain and yellow coloration of eyes. Her
serum
bilirubin -15mg/dl Vanderberg test was direct positive and
serum
alkaline phosphatase was 50 IU.
- Give the most appropriate name of this clinical condition.
- What is the life span of RBC and how do you measure it ?
- List the steps of breakdown of Hemoglobin (1+3+6=10 marks)
2. An 8 year old boy presented with swelling of knee joint
following a fall. He gave a past history of repeated episodes of bleeding after
minor injuries. Blood investigations showed bleeding time-20 min, platelet count-3 lakhs/cumm. Based on these
findings a diagnosis of Hemophilia was made.
- Name the different types and their causes
- Comment on the investigations giving their normal values
- What is the treatment (1.5+1.5+6+1=10 marks)
3. A 30 years old women visits a clinic with the complaints
of difficulty in breathing and fatigue.She has menorrhagia for the past 3
months.Her Hb level is 6gm%,PCV20% and MCV is 62 cubic micron. Answer the
following:
- Name the clinical condtion.
- Describe the blood picture in this condition.
- Classify anemia based on etiology.
- Describe iron deficiency anemia. (1+2+3+4=10)