MODEL
QUESTION PAPER
First Professional MBBS Degree
Examination
Paper - I BIOCHEMISTRY
Time: 3 hrs Max marks: 50
Instructions:
• Draw
diagrams wherever necessary
• Answer all
questions.
1. Name the
sulphur containing amino acid. Discuss metabolism of
the essential
amino acid of this group and add a note on associate
inborn
errors. (1+5+4=10 marks)
Discuss the following:
2.
Complication of Diabetes mellitus
3. Components
and sequence of reactions occur in Electron transport
chain. (2x5 =10 marks)
Write short notes on:
4. Structure
of human insulin.
5. Structure
of bio membrane.
6. Fatty acid
synthase enzyme complex.
7. Glycation
of haemoglobin and it's significances.
8. What is
the Normal serum cholesterol? Why HDL & LDL
cholesterol
are known as good and bad cholesterol respectively ?( 5x3 =15 marks)
Write briefly:
9. Key
enzymes of gluconeogenesis.
10. Energy
expenditure in Urea cycle.
11.
Importance of Carnitine in lipid metabolism
12. Deficient
enzyme and clinical features in galactosemia.
13. What is
the biochemical basis of fatty liver in alcoholism? (5x2
=10 marks)
Give precise answers:
14. What is
the basis of curdling of milk?
15. Mention
any four fate of acetyl CoA.
16. Mention
any two functions of phospholipids.
17. Mention
any two enzymes used as therapeutic agents
18. Why
sample for glucose estimation is collected in a fluoride
bottle? (5x1 =5 marks)