Friday, 5 June 2015

AIPGMEE 2005 QUESTION PAPER WITH ANSWERS- GENERAL MEDICINE



Q76: Antibiotic treatment of choice for treating cholera in an adult is a single dose of ?
A) Tetracycline
B) Co-trimoxazole
C) Doxycycline
D) Furazolidone

Answer: C) Doxycycline

Q77: For the treatment of case of class III dog bite, all of the following are correct except ?
A) Give Immunoglobins for positive immunity
B) Give ARV
C) Immediately stitch wound under antibiotic coverage
D) Immediately wash wound with soap and water

Answer: C) Immediately stitch wound under antibiotic coverage

Q78: A 59 year old man with severe myxomatous mitral regurgitation is asymptomatic, with a left ventricular ejection fraction of 45% and an end-systolic diamater index of 2.9 cm/m2. The most appropriate treatment is ?
A) Mitral valve repair or replacement
B) No treatment
C) ACE inhibitor therapy
D) Digoxin and diuretic therapy

Answer: A) Mitral valve repair or replacement

Q79: Palpable purpura could occur in the following conditions, except ?
A) Thrombocytopenia
B) Small-vessel vasculitis
C) Disseminated gonococcal infection
D) Acute meningococcemia

Answer: A) Thrombocytopenia

Q80: A 30 years old male patient presents with complaints of weakness in right upper and both lower limbs for last 4 months. He developed digital infarcts involving 2nd and 3rd fingers on right side and 5th finger on left side. On examination, BP was 160/140 mm Hg, all peripheral pulses were palpable and there was asymmetrical neuropathy. Investigations showed a Hb-12gm, TLC-12000Cu mm, Platelets 4,30,000, ESR- 49 mm. Urine examination showed proteinuria and RBC 10 - 15 /hpf with no casts. Which of the following is the most likely diagnosis ?
A) Polyarteritis nodosa
B) Systemic lupus erythematosus
C) Wegener's granulomatosis
D) Mixed cryoglobulinemia

Answer: A) Polyarteritis nodosa

Q81: Which of the following infestation leads to malabsorption ?
A) Giardia lamblia
B) Ascaris lumbricoides
C) Necator americana
D) Ancyclostoma duodenale

Answer: A) Giardia lamblia

Q82: All of the following can cause osteoporosis, except ?
A) Hyperparathyroidism
B) Steroid use
C) Fluorosis
D) Thyrotoxicosis

Answer: C) Fluorosis

Q83: Serum angiotensin converting enzyme may be raised in all of the following except ?
A) Sarcoidosis
B) Silicosis
C) Berylliosis
D) Bronchogenic carcinoma

Answer: D) Bronchogenic carcinoma

Q84: Hypercalcemia associated with malignancy is most often mediated by ?
A) Parathyroid hormone (PTH)
B) Parathyroid hormone related protein (PTHrP)
C) Interleukin - 6 (IL-6)
D) Calcitonin
Answer: B) Parathyroid hormone related protein (PTHrP)

Q85: All of the following are the causes of relative polycythemia except ?
A) Dehydration
B) Dengue haemorrhagic fever
C) Gaisbock syndrome
D) High altitude
Answer: D) High altitude

Q86: All of the following may cause ST segment elevation on EKG, except ?
A) Early repolarization variant
B) Constrictive pericarditis
C) Ventricular aneurysm
D) Prinzmetal angina
Answer: B) Constrictive pericarditis

Q87: 5' - Nucleotidase activity is increased by ?
A) Bone diseases
B) Prostate cancer
C) Chronic renal failure
D) Cholestatic disorders
Answer: D) Cholestatic disorders

Q88: Normal CSF glucose level in a normoglycemic adult is ?
A) 20 - 40 mg/dL
B) 40 - 70 mg/dL
C) 70 - 90 mg/dL
D) 90 - 110 mg/dL
Answer: B) 40 - 70 mg/dL

Q89: Bart's hydrops fetalis is lethal because ?
A) Hb Bart's cannot bind oxygen
B) The excess á - globin form insoluble precipitates
C) Hb Bart's cannot release oxygen to fetal tissues
D) Microcytic red cells become trapped in the placenta
Answer: C) Hb Bart's cannot release oxygen to fetal tissues

Q90: Cluster headache is characterized by all, except ?
A) Affects predominantly females
B) Unilateral headache
C) Onset typically in 20 - 50 years of life
D) Associated with conjunctival congestion
Answer: A) Affects predominantly females

Q91: The most sensitive test for the diagnosis of myasthenia gravis is ?
A) Elevated serum Ach-receptor binding antibodies
B) Repetitive nerve stimulation test
C) Positive edrophonium test
D) Measurement of jitter by single fibre electromyography
Answer:D) Measurement of jitter by single fibre electromyography

Q92: Vitamin B12 deficiency can give rise to all of the following except ?
A) Myelopathy
B) Optic atrophy
C) Peripheral neuropathy
D) Myopathy
Answer: D) Myopathy

Q93: EEG is usually abnormal in all of the following except ?
A) Subacute sclerosing panencephalitis
B) Locked - in state
C) Creutzfeldt - Jackob disease
D) Hepatic encephalopathy
Answer: B) Locked - in state

Q94: All of the following are neurologic channelopathies except ?
A) Hypokalemiac periodic paralysis
B) Episodic ataxia type I
C) Familial hemiplegic migraine
D) Spinocerebellar ataxia I
Answer: D) Spinocerebellar ataxia I

Q95: All of the following conditions are known to cause diabetes insipidus except ?
A) Multiple sclerosis
B) Head injury
C) Hisitiocytosis
D) Viral encehalitis
Answer: A) Multiple sclerosis

Q96: Antipsychotic drug-induced parkinsonism is treated by ?
A) Anticholinergics
B) Levodopa
C) Selegiline
D) Amantadine
Answer: A) Anticholinergics

Q97: Which one of the following is used in therapy of Toxoplasmosis ?
A) Artensenuate
B) Thiacetazone
C) Ciprofloxacin
D) Pyrimethamine
Answer: D) Pyrimethamine

Q98: Which of the following drugs is useful in prophylaxis of migraine ?
A) Propranolol
B) Sumatriptan
C) Domperidone
D) Ergotamine
Answer: A) Propranolol

Q99: The most common pathogens responsible for nosocomial pneumonias in the ICU are ?
A) Gram positive organisms
B) Gram negative organisms
C) Mycoplasma
D) Virus infections
Answer: B) Gram negative organisms

Q100: A 50 year old man, an alcoholic and a smoker presents with a 3 hour history of severe retrosternal chest pain and increasing shortness of breath. He started having this pain while eating, which was constant and radiated to the back and interscapular region. He was a known hypertensive. On examination, he was cold and clammy with a heart rate of 130/min, and a BP of 80/40 mm Hg. JVP was normal. All peripheral pulses were present and equal. Breath sounds were decreased at the left lung base and chest x-ray showed left pleural effusion. Which one of the following is the most likely diagnosis ?
A) Acute aortic dissection
B) Acute myocardial infarction
C) Rupture of the esophagus
D) Acute pulmonary embolism
Answer: A) Acute aortic dissection

Q101: Which of the following is a cause of reversible dementia ?
A) Subacute combined degeneration
B) Picks disease
C) Creutzfeldt - Jakob disease
D) Alzheimer's disease
Answer: A) Subacute combined degeneration

Q102: The following bacteria are most often associated with acute neonatal meningitis except ?
A) Escherichia coli
B) Streptococcus agalactiae
C) Neisseria meningitidis
D) Listeria monocytogenes
Answer: C) Neisseria meningitidis

Q103: Atypical pneumonia can be caused by the following microbial agents except ?
A) Mycoplasma pneumoniae
B) Legionella pneumophila
C) Human Corona virus
D) Klebsiella pneumoniae
Answer: D) Klebsiella pneumoniae

Q104: The most common organism amongst the following that causes acute meningitis in an AIDS patient is ?
A) Stretococus pneumoniae
B) Streptococcus agalactiae
C) Cryptococcus neoformans
D) Listeria monocytogenes
Answer: C) Cryptococcus neoformans

Q105: A bacterial disease that has been associated with the 3
A) Leptospirosis
B) Plague
C) Melioidosis
D) Rodent-bite fever
Answer: A) Leptospirosis

Q106: Which one of the following is true of adrenal suppression due to steroid therapy ?
A) It is not associated with atrophy of the adrenal glands
B) It does not occur in patients receiving inhaled steroids
C) It should be expected in anyone receiving > 5mg, Prednisolone daily
D) Following cessation, the stress response normalises after 8 weeks
Answer: C) It should be expected in anyone receiving > 5mg, Prednisolone daily

Q107: Pancreatitis, pituitary tumor and phaeochromocytoma may be associated with ?
A) Medullary carcinoma of thyroid
B) Papillary carcinoma of thyroid
C) Anaplastic carcinoma of thyroid
D) Follicular carcinoma of thyroid
Answer: A) Medullary carcinoma of thyroid