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Friday 5 June 2015

AIPGMEE 2005 QUESTION PAPER WITH ANSWERS- MICROBIOLOGY



Q108: With reference to infections with Escherichia coli the following are true except ?
A) Enteroaggregative E.coli is associated with Persistent diarrhoea
B) Enterohemorrhagic E.coli can cause haemolytic uraemic syndrome
C) Enteroinvasive E.coli produces a disease similar to salmonellosis
D) Enterotoxigenic E.coli is a common cause of traveler's diarrhoea

Answer: C) Enteroinvasive E.coli produces a disease similar to salmonellosis

Q109: The following statements are true regarding melioidosis except ?
A) It is caused by Burkholderia mallei
B) The agent is a gram negative aerobic bacteria
C) Bipolar staining of the aetiological agent is seen with methylene blue stain
D) The most common form of melioidosis is pulmonary infection

Answer: A) It is caused by Burkholderia mallei

Q110: All of the following Vibrio sp. are halophilic, except ?
A) V.cholerae
B) V.parahaemolyticus
C) V.alginolyticus
D) V.fluvialis

Answer: A) V.cholerae

Q111: All of the following organisms are known to survive intracellularly except ?
A) Neisseria meningitides
B) Salmonella typhi
C) Streptococcus pyogenes
D) Legionella pneumophila

Answer: C) Streptococcus pyogenes

Q112: The capsule of Cryptococcus neoformans in a CSF sample is best seen by ?
A) Grams stain
B) India ink preparation
C) Giemsa stain
D) Methanamine - Silver stain

Answer: B) India ink preparation

Q113: Viruses can be isolated from clinical samples by cultivation in the following except ?
A) Tissue culture
B) Embryonated eggs
C) Animals
D) Chemically defined media

Answer: D) Chemically defined media

Q114: It is true regading the normal microbial flora present on the skin and mucous membranes that ?
A) It cannot be eradicated by antimicrobial agents
B) It is absent in the stomach due to the acidic pH
C) It establishes in the body only after the neonatal period
D) The flora in the small bronchi is similar to that of the trachea

Answer: A) It cannot be eradicated by antimicrobial agents

Q115: An army jawan posted in a remote forest area had fever and headache. His fever was 104°F and pulse was 70 per min. He had an erythematous lesion of about 1 cm on the leg surrounded by small vesicles, along with generalized lymphadenopathy at the time of presentation to the referral hospital. His blood sample was collected to perform serology for the diagnosis of Rickettsial disease. Which one of the following results in Weil-felix reaction will be diagnostic in this clinical setting ?
A) High OX-2
B) High OX-19
C) High OX-K
D) High OX-19 and OX-2

Answer: C) High OX-K

Q116: Adenosine deaminase (enzyme) deficiency is associated with ?
A) Severe combined immunodeficiency (SCID)
B) X-linked agammaglobulinemia
C) Transient hypogammaglobulinemia of infancy
D) Chronic granulomatous disease

Answer: A) Severe combined immunodeficiency (SCID)

Q117: The serum concentration of which of the following human IgG subclass is maximum ?
A) IgG1
B) IgG2
C) IgG3
D) IgG4

Answer: A) IgG1

Q118: Chlamydia trachomatis is associated with the following except ?
A) Endemic trachoma
B) Inclusion conjunctivitis
C) Lymphogranuloma venereum
D) Community acquired pneumonia

Answer: D) Community acquired pneumonia

Q119: The following statements are true regarding Clostridium perfringens except ?
A) It is the commonest cause of gas gangrene
B) It is normally present in human faeces
C) The principal toxin of C.perfringens is the alpha toxin
D) Gas gangrene producing strains of C.perfringens produce heat resistant spores

Answer: D) Gas gangrene producing strains of C.perfringens produce heat resistant spores

Q120: A child was diagnosed to be suffering from diarrhoea due to Camplyobacter jejuni. Which of the following will be the correct enviornmental conditions of incubation of the culture plates of the stool sample ?
A) Temperature of 42°C and microaerophilic
B) Temperature of 42°C and 10% carbondioxide
C) Temperature of 37°C and microaerophilic
D) Temperature of 37°C and 10% carbondioxide

Answer: A) Temperature of 42°C and microaerophilic

Q121: Which one of the following statements is true regarding Chlamydia pneumoniae ?
A) Fifteen serovars have been identified as human pathogens
B) Mode of transmission is by the airborne bird excreta
C) The cytoplasmic inclusions present in the sputum specimen are rich in glycogen
D) The group specific antigen is responsible for the production of complement fixing antibodies

Answer: D) The group specific antigen is responsible for the production of complement fixing antibodies

Q122: Virus mediated transfer of host DNA from one cell to another is known as ?
A) Transduction
B) Transformation
C) Transcription
D) Integration

Answer: A) Transduction

Q123: HIV can be detected and confirmed by ?
A) Polymerase Chain Reaction (PCR)
B) Reverse Transcriptase - PCR
C) Real Time PCR
D) Mimic PCR

Answer: B) Reverse Transcriptase - PCR

Q124: In the small intestine, cholera toxin acts by ?
A) ADP-ribosylation of the G regulatory protein
B) Inhibition of adenyl cyclase
C) Activation of GTPase
D) Active absorption of NaCl

Answer: A) ADP-ribosylation of the G regulatory protein



Q124: Which of the following is not a neuroparasite ?
A) Taenia solium
B) Acanthamoeba
C) Naegleria
D) Trichinella spiralis

Answer: D) Trichinella spiralis