HEMATOLOGY- CASES, ESSAYS AND SHORT NOTES- 4TH MBBS KUHS

ESSAYS

1. A 60 years lady presents with tingling, fatigue and passing dark tarry foul smelling stools.On examination, severe pallor was present and ejection systolic murmur at the pulmonary area. Answer the following

• What is your probable diagnosis
• What are the probable causes for this condition
• How will you confirm the diagnosis
• How will you treat this condition (2+3+2+3)

2. A 24 years old woman presents with purpuric rash on her lower limbs, bleeding from gums while brushing since two weeks. She denies menorrhagia or hematuria. No history of preceding fever or upper respiratory tract infection. No history of taking NSAID or any other medications. Answer the following

•  What are your differential diagnosis
•  How do you investigate
•  How do you treat. (2+4+4=10)

3. A 65 years old woman comes with general malaise, tiredness since six months and two months history of shortness of breath on moderate exertion. She c/o, sore tongue, pins and needles sensation in her feet. Her blood smear shows macrocytic anemia and thrombocytopenia. Answer the following

•  What are your differential diagnosis
•  What further investigations you do.
•  Describe the peripheral and bone marrow picture of megaloblastic anemia.
•  How do you treat. (2+2+3+3=10)

4. 40 years old alcoholic vegetarian comes to out- patient department with history of fatigue, weakness and exertional breathlessness. On examination patient is anemic with red beefy tongue and knuckle pigmentation. Answer the following

•  What is your likely diagnosis and cause for knuckle pigmentation.
•  What are the likely causes and mechanism of this condition.
•  How will you investigate this patient.
•  How do you manage this patient. (2+2+3+3=10)

SHORT NOTES

1. Polycythemia vera
2. Immune thrombocytopenia
3. International normalized ratio (INR
4. Clinical features of acute intermittent porphyria
5. Myelodysplastic syndrome
6. Treatment of thalassemia
7. Factor VIII replacement in hemophilia A
8. Treatment of iron deficiency anemia
9. Differential diagnosis of macrocytic anemia
10. Hypochromic microcytic anemia
11. Differential diagnosis of microcytic anemia
12. Sickle cell crisis
13. Risk factors of deep vein thrombosis
14. Treatment of chronic myeloid leukemia
15. Complications of blood transfusion
16. Platelet rich plasma