Q.P. Code: 202001 Reg. no.: …………
Second Professional MBBS Degree Examinations February 2019
Pharmacology - Paper II
Time: 2 Hours Max. Marks: 40
Answer all questions Draw diagrams wherever necessary
Essays (2x6=12)
1. Read the case history and answer the following questions: A 25 years old lady
reported to the hospital with complaints of low grade fever since 10 days and
weakness, fatigue, cough & expectoration since one month. Sputum was found to be
positive for AFB and X-ray chest showed fibrotic changes in the left upper lobe.
(2+2+2)
What is the treatment regimen to be followed for the patient
Explain the mechanism of action and adverse effects of Rifampicin
What would you advise if the lady was pregnant
2. Classify corticosteroids. Describe the uses and adverse effects of glucocorticoids
(2+2+2)
Short Notes (5x3=15)
3. Clarithromycin
4. Methotrexate
5. Protease inhibitors
6. Ondansetron
7. Insulin Glargine
Write the Pharmacological basis for the use of: (3x1=3)
8. Penicillamine in Wilson’s disease
9. Amoxicillin with clavulanic acid
10.Lansoprazole, amoxicillin and clarithromycin in H. pylori infection
Write two uses and two adverse effects of the following: (3x1=3)
11.Raloxifene
12.Metronidazole
13.Chloroquine
Choose the appropriate drug and Justify: (2x1=2)
14.Griseofulvin / Miconazole in candida albicans
15.Ciprofloxacin / Amoxicillin in urinary tract infection in pregnancy
Name the following (Two examples for each) (5x1=5)
16.Vinca alkaloids in cancer chemotherapy
17.Anti-seborrheic agents
18.Proton pump inhibitors
19.Drugs effective against both gram positive & gram negative organisms
20.Antithyroid drugs
