Q.P. Code: 201001 Reg. No.: …….....
Second Professional MBBS Degree Examinations February 2019
Pharmacology - Paper I
Time: 2 Hours Max Marks: 40
- Answer all questions
- Draw diagrams wherever necessary
Essays: (2x6=12)
1. Enumerate the topical group of agents used in the treatment of open angle glaucoma. Give examples and explain the mechanism of action of each group of drugs. (2+2+2)
2. 19 yrs old Saravanan was admitted to the emergency ward with the history of
consumption of poison after love failure. On admission, he had profuse sweating, excess salivation, laboured breathing & pinpoint pupil. He had thrown convulsion once. His pulse rate was 45-50/mt.
- What is your probable diagnosis
- What is the line of management
- What are the specific antidotes. How they are useful. (1+2+1+2)
Short Notes: (5x3=15)
3. Apparent volume of distribution
4. Treatment of smoking cessation
5. Cetirizine
6. Valproic acid
7. Furosemide
Write the Pharmacological basis for the use of: (3x1=3)
8. Atropine as antisecretory agent
9. Angiotensin converting enzyme inhibitor in congestive cardiac failure
10.Dantrolene in malignant hyperthermia
Write two uses and two adverse effects of the following drugs: (3x1=3)
11.Tenecteplase
12.Allopurinol
13.Haloperidol
Choose the appropriate drug and Justify: (2x1=2)
14.Naloxone / Nalbuphine in morphine poisoning
15.Lidocaine / Propranolol to treat arrhythmia following myocardial infarction
Name the following (Two examples for each): (5x1=5)
16.HMG-CoA reductase inhibitor
17.Antiplatelet agent
18.COMT inhibitor
19.Leukotriene antagonist
20.Selective serotonin reuptake inhibitor
