PATHOLOGY PAPER 1- 2ND MBBS KUHS - FEBRUARY 2015

Q.P. Code: 203001                                          Reg. no.:  ..............
Second Professional MBBS Degree Examinations, February 2015
Clinical Pathology and General Pathology- Paper I
Time: 2 Hours                                 Total Marks: 40

• Answer all questions
• Draw diagrams wherever necessary

Essay: (8)

1. Define reversible and irreversible cell injury. What is the pathogenesis of irreversible cell injury. Define and describe the type of necrosis and gangrene (1+3+4=8 )

2. A 45 years old male was admitted with complaints of yellowish discoloration of eyes and distention of abdomen since 15 days. USG abdomen shows contracted liver with loss of architecture and splenomegaly. Patient is a chronic alcoholic since 15 years. Answer the following:

• What is the most probable diagnosis
• Describe the gross and microscopic features of the organ involved
• Name the laboratory investigation to be done in this case and the expected variation in this values
• List three complications of the above condition

Short notes: (4×4=16)
3. Erythrocyte sedimentation rate
4. Pathogenesis of amyloidosis
5. Staining of peripheral blood film
6. Transudate and exudate

Answer briefly: (4×2=8)
7. Actinomycosis
8. Pathogenesis of CNS lesions seen in HIV infection
9. Exfoliative cytology
10. Manifestations of vitamin A deficiency

Answer in single sentence: (4×0.5=2)
11. Define negative hypersensitivity reaction
12. Define fixed specific gravity
13. Define dysplasia
14. Mention two anticoagulants