Question 167:Yawning is a common feature of ?
A) Alcohol withdrawal
B) Cocaine withdrawal
C) Cannabis withdrawal
D) Opioid withdrawal
Ans:D
Question 168:Which one of the following is the shortest acting intravenous analgesic ?
A) Remifentanil
B) Fentanyl
C) Alfentanyl
D) Sufentanil
Ans:A
Question 169:The ideal muscle relaxant used for a neonate undergoing porto-enterostomy for biliary atresia is ?
A) Atracurium
B) Vecuronium
C) Pancuronium
D) Rocuronium
Ans:A
Question 170:The following statement is not true about the use of clonidine in the treatment of hypertension ?
A) Reduction in central sympathetic outflow
B) Increase in LDL-cholesterol on prolonged use
C) Sedation and xerostomia are common side effects
D) It can also be controlled with vasodilators
Ans:B
Question 171:The following statement is not true about sotalol ?
A) It is a non-selective beta-blocker
B) It prolongs action potential duration throughout the heart
C) It is excreted through bile following hepatic metabolism
D) Polymorphic ventricular tachycardia is a common side effect
Ans:C
Question 172:The following is not true about the use of beta-blockers in heart failure ?
A) It should be initiated at a very low dose
B) It is most effective in new-onset decompensated heart failure
C) Slow upward titration of dose is required
D) Carvedilol is most widely used in this condition
Ans:B
Question 173:The diuretic group that does not require access to the tubular lumen to induce diuresis is ?
A) Carbonic anhydrase inhibitor
B) Na-Cl symport inhibitor
C) Mineralocorticoid antagonist
D) Na-K symport inhibitor
Ans:C
Question 174:In a young patient who had extensive soft tissue and muscle injury, which of these muscle relaxants used for endotracheal intubation might lead to cardiac arrest ?
A) Atracurium
B) Suxamethonium
C) Vecuronium
D) Pancuronium
Ans:B
Question 175:For drugs with first-order kinetics, the time required to achieve steady state levels can be predicted from ?
A) Volume of distribution
B) Half life
C) Clearance
D) Loading dose
Ans:B
Question 176:All of the following drugs are metabolised by acetylation except ?
A) INH
B) Sulfonamides
C) Ketoconazole
D) Hydralazine
Ans:C
Question 177:A vasopressin analogue does not produce therapeutic effect through vasopressin V-2 receptor in which of the following ?
A) Central diabetes insipidus
B) Bleeding oesophageal varices
C) Type I von Willebrand's disease
D) Primary nocturnal enuresis
Ans:B
Question 178:A middle aged old man, with chronic renal failure is diagnosed to have sputum positive pulmonary tuberculosis. His creatinine clearance is 25ml/min. All of the following drug need modification in doses except ?
A) Isoniazid
B) Streptomycin
C) Rifampicin
D) Ethambutol
Ans:C
A) Alcohol withdrawal
B) Cocaine withdrawal
C) Cannabis withdrawal
D) Opioid withdrawal
Ans:D
Question 168:Which one of the following is the shortest acting intravenous analgesic ?
A) Remifentanil
B) Fentanyl
C) Alfentanyl
D) Sufentanil
Ans:A
Question 169:The ideal muscle relaxant used for a neonate undergoing porto-enterostomy for biliary atresia is ?
A) Atracurium
B) Vecuronium
C) Pancuronium
D) Rocuronium
Ans:A
Question 170:The following statement is not true about the use of clonidine in the treatment of hypertension ?
A) Reduction in central sympathetic outflow
B) Increase in LDL-cholesterol on prolonged use
C) Sedation and xerostomia are common side effects
D) It can also be controlled with vasodilators
Ans:B
Question 171:The following statement is not true about sotalol ?
A) It is a non-selective beta-blocker
B) It prolongs action potential duration throughout the heart
C) It is excreted through bile following hepatic metabolism
D) Polymorphic ventricular tachycardia is a common side effect
Ans:C
Question 172:The following is not true about the use of beta-blockers in heart failure ?
A) It should be initiated at a very low dose
B) It is most effective in new-onset decompensated heart failure
C) Slow upward titration of dose is required
D) Carvedilol is most widely used in this condition
Ans:B
Question 173:The diuretic group that does not require access to the tubular lumen to induce diuresis is ?
A) Carbonic anhydrase inhibitor
B) Na-Cl symport inhibitor
C) Mineralocorticoid antagonist
D) Na-K symport inhibitor
Ans:C
Question 174:In a young patient who had extensive soft tissue and muscle injury, which of these muscle relaxants used for endotracheal intubation might lead to cardiac arrest ?
A) Atracurium
B) Suxamethonium
C) Vecuronium
D) Pancuronium
Ans:B
Question 175:For drugs with first-order kinetics, the time required to achieve steady state levels can be predicted from ?
A) Volume of distribution
B) Half life
C) Clearance
D) Loading dose
Ans:B
Question 176:All of the following drugs are metabolised by acetylation except ?
A) INH
B) Sulfonamides
C) Ketoconazole
D) Hydralazine
Ans:C
Question 177:A vasopressin analogue does not produce therapeutic effect through vasopressin V-2 receptor in which of the following ?
A) Central diabetes insipidus
B) Bleeding oesophageal varices
C) Type I von Willebrand's disease
D) Primary nocturnal enuresis
Ans:B
Question 178:A middle aged old man, with chronic renal failure is diagnosed to have sputum positive pulmonary tuberculosis. His creatinine clearance is 25ml/min. All of the following drug need modification in doses except ?
A) Isoniazid
B) Streptomycin
C) Rifampicin
D) Ethambutol
Ans:C
