BIOCHEMISTRY PAPER II-1ST MBBS SUPPLIMENTARY EXAMINATION FEBRUARY 2014-KUHS

Q.P.Code:106001                         Reg.no:…………….
First professional MBBS Degree Supplementary Examinations, February 2014
BIOCHEMISTRY-PAPER II
Time: 3Hours                         Total Marks:50

• Answer all questions
• Draw diagrams wherever necessary

Essay (10)
1. Describe the source, dietary requirements, biochemical functions and deficiency manifestations of vitamin A (1+1+4+4=10)
Short essays (2×5=10)
2. Explain briefly on blood buffers and add a note renal mechanism of maintaining acid base balance
3. Describe the process of DNA replication
Short notes (5×3=15)
4. Abnormal hemoglobins
5. Tumor markers
6. Liver function tests
7. Immunoglobulins
8. Gene therapy
Answer briefly (5×2=10)
9. Folate antagonists
10. Normal serum concentration of sodium and potassium
11. ELISA (Enzyme Linked Immunosorbent Assay)
12. What is the normal serum calcium level? Name the hormones regulating it
13. Enzyme defect in lesch-nyhan syndrome and orotic aciduria
Give precise answers (5×1=5)
14. Deficiency of vitamin C
15. Examples for point mutation
16. What are BJP (Bence Jones Proteins)
17. Name two oncogenes
18. Normal serum uric acid level