First professional degree examinations- September 2011
BIOCHEMISTRY -PAPER 2
Time: 3 Hrs Max Marks: 50
- Answer all questions
- Draw diagrams whenever necessary
Essay: (10)
1. Describe how protein is synthesized in
body. Name any two inhibitors of protein biosynthesize. Add a note on post
translational modifications. (6+2+2=10)
Discuss
the following: (2×5=10)
2. Outline the degradation of heme. Add a
note on fate of conjugated bilirubin in intestine.
3. Write briefly on storage and absorption
of iron from intestine.
Write
short notes on: (5×3=15)
4. What is gout? Mention the causes of
primary gout.
5. What is the role of kidney in acid base regulation?
6. What are restriction endonucleases. What
are their uses?
7. Write principle and application of
polymerase chain reaction.
8. Write the structure of IgG molecule and
indicate its function.
Answer
briefly: (5×2=10)
9. Name the coenzyme forms of niacin and
write important functions of each one of them.
10. Wilsons disease.
11. What is metabolic acidosis? Give one
example of a disease associated with it.
12. Give two examples of detoxification by
conjugation.
13. What is post hepatic jaundice? How is
it diagnosed biochemically?
Give
precise answers on: (5×1=5)
14. What is provitamin . Give one example.
15. Clinical features of rickets.
16. Give one example for point mutation.
17. What are the enzymes commonly used in
ELISA Technique.
18. Xeroderma pigmentosum is due to
deficiency of what process.
