First Professional MBBS Degree Examinations- September
2011
BIOCHEMISTRY PAPER 1
Time: 3 Hrs Max Marks : 50
- Answer all questions
- Draw diagrams wherever necessary
Essay
: (10)
1. Define β-oxidation. Explain the reactions of β-oxidation of palmitic acid. Add a note on its energetics.
(2+5+3=10)
Discuss
the following: (2×5=10)
2. Define and classify enzymes. Give one
example for each class and mention the reaction catalysed.
3. Define urea cycle and describe the
reactions of urea cycle.
Write
short notes on: (5×3=15)
4. Phenylketonuria
5. Classify lipoproteins and mention the
function of each.
6. What is substrate level phosphorylation
and mention two examples.
7. Define transamination and give two
examples
8. Define HMP shunt pathway and mention its
significance.
Answer
briefly: (5×2=10)
9. Name two plasma transport proteins and
mention their role.
10. Mention two glycogen storage diseases
with their deficient enzyme.
11. Write the clinical significance of
glycated haemoglobin estimation.
12. Name the bile salts and mention its
functional significance
13. What is Gaucher’s disease? Mention two
clinical features.
Give
precise answers: (5×1=5)
14. Linkage present in sucrose
15. Name two sulphur containing amino acids
16. Mention the enzyme defect in Galactosemia
17. Mention the chemical name of lecithin
18. Define Km value.
