FIRST PROFESSIONAL
DEGREE MODEL EXAMINATION, AUGUST 2011
BIOCHEMISTRY PAPER 1
Time:3 hours Total
Marks:50
- Answer all questions
- Draw Diagrams whenever necessary
Long Essay:(10)
1. Describe
the various mechanisms by which ammonia is detoxified in the body& add a
note on urea cycle disorders(7+3=10)
Discuss the following:
(2×5=10)
2. Beta
oxidation of fatty acids
3. Regulation
of enzyme activity
Write short notes on:
(5×3=15)
4.
Homocystinurias
5.
Significance of HMP shunt pathway
6. Glucose
transporters
7. Protein
energy malnutrition*/Plasma lipid profile**
8. Diagnosis
and monitoring of diabetes mellitus
Write briefly: (5×2=10)
9. Ionophores*/Transamination**
10.
Physiologic uncouplers
11. PUFA
12.
Polyamines
13.
Glycosaminoglycans
Give precise answers : (5×1=5)
14. VMA
15. Rf
value*/Phosphatidic acid**
16. Rate
limiting reaction of cholesterol biosynthesis
17. Give the
normal serum values of
- CPK-MB
- HDL
18. Name the
enzyme deficient in:
- Von Gierke's disease
- Niemann Pick disease
*Question changed by KUHS at the time of examination
**New question instead of the changed one
