Q.P. Code: 202001 Reg. no.: …………………
Second Professional MBBS Degree Supplementary Examinations,
August 2017
Pharmacology- Paper II
Time: 2 Hours Total Marks: 40
• Answer all questions• Draw diagrams wherever necessary
1. Classify oral hypoglycemic agents. Explain the mechanism
of action and adverse effects of any one group. (2+2+2)
2. A 20 years old pregnant women developed a mild bacterial
upper respiratory tract infection. She was given cap. tetracycline 250 mg
thrice daily for 3 days. Answer the following questions:
- Comment on the treatment for a mild bacterial infection
- Comment on the use of tetracycline in pregrarcy
- If it were a severe infection what would be the choice of antibiotic in a pregnant woman. (2+2+2)
Short notes:
3. 4th generation cephalosporins
4. Metronidazole
5. Chloroquine
6. Bisphosphonates
7. Clomiphene citrate
Answer briefly: (5x1=5)
8. Mechanism of action of INH
9. Rationale for the use of combination of drugs in cancer
chemotherapy
10. Pharmacological basis for the use of thalidomide in
lepra reaction
11. Anti- thyroid drugs safe during pregnancy
12. Rationale for the use of folinic acid in methotrexate
overdose
Name two drugs: (8x1 =8)
13. Treatment of MDR-TB
14. Post exposure prophylaxis of HIV (acquired
immunodeficiency syndrome)
15. Treatment of acne vulgaris
16. Prophylaxis of rheumatic fever
17. Insulin analogues
18. Proton pump inhibitors
19. Topical antifungal agents
20. Anabolic steroids
