Second Professional MBBS Degree Supplementary Examinations,
August 2017
Pharmacology- Paper I
Time: 2 Hours Total Marks: 40
• Answer all questions• Draw diagrams wherever necessary
Essays: (2x6=12)
1. Enumerate five groups of anti- hypertensive drugs with
examples of each . Discuss the mechanism of action, adverse effects and
therapeutic uses of any one of them. (2+2+1+1)
2. Read the clinical problem and answer the following
questions:
After injection of succinylcholine i.v. to provide muscle
relaxation, the patient developed prolonged apnea.
- What is the probable reason for this.
- Can edrophonium be given as antidote. If yes, why and if not why not.
- What is the line of treatment. (2+2+2=6)
3. Neostigmine.
4. Propofol.
5. Clopidogrel.
6. Physiological antagonism
7. Furosemide.
Answer briefly:
8. Two advantages and two disadvantages of i.v. route of
drug administration.
9. Explain the rationale for the use of oximes in
organophosphorus poisoning.
10. Mechanism of action of nitrates.
11. Explain the pharmacological basis for the use of ethyl alcohol
in methanol poisoning.
12. Mention two selective Cox-2 inhibitors
Name two drugs:
13. Pro 6rogs
14. H1 receptor blockers
15. Anti- muscarinic drugs
16. Teratogenicity
17. Treatment of iron deficiency anemia
18. Selective alpha blockers
19. Selective serotonin reuptake inhibitors
20. Pre- anesthetic medication
