Sunday, 7 January 2018

PHARMACOLOGY PAPER 1- 2ND MBBS KUHS-2016 OCTOBER


Q.P. Code: 201001                          Reg. no.: …………………
Second Professional MBBS Degree Supplementary Examinations,
October 2016
Pharmacology- Paper I
Time: 2 Hours                                                    Total Marks: 40
• Answer all questions
• Draw diagrams wherever necessary

Essays: (2x6=12)

1. Classify NSAIDs. Mention the therapeutic uses and adverse effects of salicylates. (2+2+2=6)
2. Read the case history and answer the following questions. A 25 years old man had a gradual
onset of delusions and auditory hallucinations. He was taken to a psychiatrist who started
him on tab. haloperidol 2mg twice daily. A few weeks later although he improved clinically he
developed stiffness and rigidity of upper and lower limbs.

• Comment on the response of the patient to haloperidol.
• Outline the further line of management.
• Name two atypical antipsychotics. (2+2+2=6)

Short notes: (5x3=15)

3. Carvedilol
4. COMT inhibitors.
5. Therapeutic uses and adverse effects of atropine.
6. Furosemide.
7. First pass metabolism.

Answer briefly: (5x1=5)

8. Rationale for the use of glycopyrrolate in pre-anesthetic medication.
9. Mechanism of action of pancuronium.
10. New drug delivery systems.
11. Two uses and two adverse effects of morphine.
12. Young’s formula.

Name two drugs: (8x1=8)

13. Status epilepticus.
14. Febrile convulsions in a child aged six years.
15. Drugs used in myasthenia gravis.
16. Acute myocardial infarction.
17. Congestive cardiac failure.
18. Iron deficiency anemia.
19. Motion sickness.
20. Acute severe asthma.