Q.P.Code
106001 Reg. No.:…………………
First Professional MBBS Degree Examinations -
August 2015
BIOCHEMISTRY -
PAPER II
Time : 3 hrs Max
marks : 50
•
Answer all
questions
•
Draw diagrams
wherever necessary
Essay (10)
1. Describe
the process of transcription. What are the post transcriptional modifications.
Mention two inhibitors of transcription. (6+3+1=10)
Short essays (2x5=10)
2.
Describe uric acid formation and mention the
clinical significance of its estimation.
3. Mention
the normal level of serum calcium. Explain the hormonal regulation of serum
calcium
Short notes (5x3=15)
4.
Acute intermittent porphyrias.
5.
Mention the normal sodium level and clinical
manifestation of hyponatremia.
6.
Applications of radio activity.
7.
Metabolic acidosis.
8. Creatinine
clearance test.
Answer briefly (5x2=10)
9.
List two reactions where the folic acid is the
co-enzyme.
10. Principles
of colorimetry.
11. How
benzoic acid and sulfanilamide are detoxified in human body.
12. Explain
why edema develops in hypo albuminemia.
13. List the
different classes of immunoglobulins and mention the functional role of any
one.
Give precise answers
(5x1=5)
14. List
anti vitamins and mention one example.
15. Co-enzyme
functions of biotin.
16. Name
two biochemical markers of cancer.
17. Reverse
transcriptases.
18. Proto-oncogenes.
