Q.P.Code
105001 Reg. No.:…………………
First Professional MBBS Degree Examinations -
August 2015
BIOCHEMISTRY -
PAPER I
Time : 3 hrs Max
marks : 50
•
Answer all
questions
•
Draw diagrams
wherever necessary
Essay (10)
1. Enumerate the components of electron transport chain.
Describe the synthesis of
ATP. Indicate the site specific
inhibitors. Mention two examples for uncouplers.
(4+2+2+2=10)
Short essays (2x5=10)
2.
Gluconeogenesis
3.
Diagnostic significance of serum enzymes
Short notes (5x3=15)
4.
Digestion of carbohydrates
5.
Essential fatty acids
6.
Denaturation
7.
Principle of chromatography
8.
Name three glycogen storage diseases and its
biochemical defect
Answer briefly (5x2=10)
9.
Role of carnitine
10. Define
isoelectric pH. State properties of a protein at its isoelectric pH
11. Importance
of HMP shunt pathway
12. Sources
of ammonia
13. Allosteric
enzymes
Give precise answers: (5x1=5)
14. Name
the biochemical defect in Nieman-pick disease
15. Zymogen
activation
16. Mention
the reaction catalyzed by ATP-citrate lyase
17. Mention
two biologically active peptides
18. Mention
one therapeutic use of enzyme
