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Saturday 20 June 2015

PATHOLOGY- AIPGMEE 2006 QUESTIONS WITH ANSWERS



Q56.the prognosis of rhabdomysarcoma is likely to be poor if the site of the tumour is:

A.     Orbit

B.     Para testicular

C.     Extremity

D.     Urinary bladder.

Ans: C.   Extremity

Q57.Which of the following malignant tumors is radioresistant?

A.     Ewing’s sarcoma.

B.     Retinoblastoma.

C.     Osteosarcoma

D.     Neuroblastoma.

Ans: C.   Osteosarcoma

Q56.The most common second malignancy in survivors of retinoblastoma is:

A.     Thyroid cancer.

B.     Nasopharyngeal carcinoma

C.     Optic glioma.

D.     Osteosarcoma.

Ans: D.  Osteosarcoma.

Q57.The most important determinant of prognosis in Wilms tumor

A.     Stage of disease.

B.     Loss of heterozygosity of chromosome 1p.

C.     Histology.

D.     Age less than one year at presentation.

Ans: C.   Histology.

Q58.The finnish type of congenital nephrotic syndrome occurs due to gene mutations affecting the following protein.

A.     Podocin

B.     Alpha-actinin

C.     Nephrin

D.     CD2 activated protein.

Ans:

Q59.Sensorineural deafness may be feature of all, except:

A.     Nail patella syndrome

B.     Distal renal tubular acidosis.

C.     Bartter syndrome.

D.     Alport syndrome.

Ans: B.   Distal renal tubular acidosis.

Q60.Drug induced lupus can be identified by

A.     Anti-histone antibodies.

B.     Double stranded DNA antibodies.

C.     Antinuclear antibodies.

D.     Anti-SM antibodies.

Ans: A.   Anti-histone antibodies.

Q61.The process underlying differences in expression of a gene, according to which parent has transmitted, is called:


A.     Anticipation

B.     Mosaicism

C.     Non-penetrance

D.     Genomic imprinting.

Ans: D.  Genomic imprinting.