Q.P.Code 106001 Reg. No.:…………
First Professional MBBS Degree Regular/Supplementary Examinations
August 2019
Biochemistry - Paper II
Time: 3 hrs Max marks: 50
- Answer all questions
- Draw diagrams wherever necessary
Essay (7+3)
1. Describe heme synthesis and its regulation in detail.
Short essays (2x5=10)
2. Post transcriptional modifications.
3. Homeostasis of blood calcium
Short notes (5x3=15)
4. DNA polymerases
5. Wilson’s disease
6. Lesch Nyhan syndrome.
7. Lac operon.
8. Radioimmunoassay
Answer briefly (5x2=10)
9. Folate trap.
10.Biochemical role of thiamine pyrophosphate
11.Pellagra.
12.Detoxification by conjugation
13.Inhibitors of translation.
Give precise answers (5x1=5)
14.Clinical features of fluorosis.
15.Hyponatremia
16.Anion gap.
17.Mention two examples of oncogenes / proto oncogenes and their associated cancer.
18.Clinical significance of bile salts