This section contains chapter wise arrangement of Previously asked questions in MBBS Degree Examinations conducted by KUHS (Kerala University of Health Sciences)
- Describe by a flow diagram the reactions of glycolysis giving names of enzymes involved. Explain its regulation and add a note on the energetic in aerobic & anaerobic conditions. (6+2+2=10)
- Enumerate irreversible steps of glycolysis with the enzymes involved/ Mention any two key enzymes of glycolysis
- Explain in detail glycogenesis and glycogenolysis. Mention the enzyme defects in any two of glycogen storage disorders (4+4+2=10)
- Define HMP shunt pathway and mention its significance/Significance of HMP shunt pathway/ Importance of HMP shunt pathway
- Trace the pathway of gluconeogenesis starting from alanine/ Glucose Alanine cycle. Mention its significance. Mention the key enzymes and how they are regulated. (5+3+2=10)
- Define gluconeogenesis. Name the gluconeogenic substrates
- Kreb’s cycle
- Name two carbon dioxide releasing steps in the TCA cycle/ Why TCA cycle is called amphibolic
- Describe glycogen metabolism
- Complication of Diabetes mellitus
- Diagnosis and monitoring of diabetes mellitus
- Structure of human insulin/ Discuss the primary structure of human insulin
- Glycation of haemoglobin and it's significances
- Gluconeogenesis/ Discuss the significance of gluconeogenesis
- Key enzymes of gluconeogenesis
- Deficient enzyme and clinical features in galactosemia
- Enzyme defect in lactose intolerance
- Glucose transporters
- Glycosaminoglycans/ What are glycosamino glycans. List two examples with its functions?
- Mention two glycogen storage diseases with their deficient enzyme
- Name the enzyme deficient in Von Gierke's disease
- What is Gaucher’s disease? Mention two clinical features
- Mention the enzyme deficient in Tay Sach’s disease
- Cori’s cycle/Enzyme deficiency in Cori’s disease
- Enzyme deficiency in Mc Ardle syndrome
- Linkage present in sucrose
- Classification of glycolipids
- Mutarotation
- What are epimers?/Epimer of glucose
- Important product of Rapaport Lubering cycle in RBC/ List the functions of Rapaport Lubering cycle
- Fate of pyruvate
- Lactose intolerance
- Mention the reaction catalyzed by ATP-citrate lyase
- Invert sugar
- Essential pentosuria
- Substrate level phosphorylation
- Mention the biochemical defect in fructosuria
- What is HbA1C and mention its clinical importance
- Why sample for glucose estimation is collected in a fluoride bottle
- Why starch can be utilized by humans but not cellulose
- Two co-enzyme roles of NADPH
- Normal blood level of urea and glucose
- Benedict’s test
