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Sunday 21 February 2016

LIBIDO

Libido (sex drive) is a person's overall sexual drive or desire for sexual activity. Sex drive is influenced by biological, psychologicalb and social factors.

 Biologically, the sex hormones and associated neurotransmitters that act upon the nucleus   accumbens (primarily testosterone and dopamine, respectively) regulate libido in men and women.
Social factors, such as work and family, and internal psychological factors, like personality and stress, can affect libido.
 Sex drive can also be affected by medical conditions, medications,  lifestyle and relationship issues, and age (e.g., puberty).
 A person who has   extremely frequent or a suddenly increased sex drive may be experiencing hypersexuality.


A person may have a desire for sex, but not have the opportunity to act on that desire, or may on personal, moral or religious reasons refrain from acting on the urge.
Psychologically, a person's urge can be repressed or sublimated.
On the other hand, a person can engage in sexual activity without an actual desire for it. Multiple factors affect human sex drive, including stress, illness, pregnancy, and others.

Sexual desires are often an important factor in the formation and maintenance of intimate relationships in both men and women.
 A lack or loss of sexual desire can adversely affect relationships. Changes in the sexual desires of either partner in a sexual relationship, if sustained and unresolved, may cause problems in the relationship. The infidelity of a partner may be an indication that a partner's changing sexual desires can no longer be satisfied within the current relationship. Problems can arise from disparity of sexual desires between partners, or poor communication between partners of sexual needs and preferences.

A person is sex starved or sexually frustrated when they have a strong sexual appetite but is sexually frustrated because of a lack of outlet or companion to release their sexual tension.

Factors that affect libido

Endogenous compounds

Libido is governed primarily by activity in the mesolimbic dopamine pathway (ventral tegmental area and nucleus accumbens).
Consequently, dopamine and related trace amines (primarily phenethylamine) that modulate dopamine neurotransmission play a critical role in regulating libido.

Other neurotransmitters, neuropeptides, and sex hormones that affect sex drive by modulating activity in or acting upon this pathway include:

Testosterone (directly correlated)
 androgens Estrogen (directly correlated)
 Progesterone (inversely correlated)
Oxytocin (directly correlated)
Serotonin  (inversely correlated)
Norepinephrine Acetylcholine

Sex hormone levels and the menstrual cycle

A woman's desire for sex is correlated to her menstrual cycle, with many women experiencing a heightened sexual desire in the several days immediately before ovulation, which is her peak fertility period, which normally occurs two days before until two days after the ovulation. This cycle has been associated with changes in a woman's testosterone levels during the menstrual cycle. According to Gabrielle Lichterman, testosterone levels have a direct impact on a woman's interest in sex. According to her, testosterone levels rise gradually from about the 24th day of a woman's menstrual cycle until ovulation on about the 14th day of the next cycle, and during this period the woman's desire for sex increases consistently. The 13th day is generally the day with the highest testosterone levels. In the week following ovulation, the testosterone level is the lowest and as a result women will experience less interest in sex.

Also, during the week following ovulation, progesterone levels increase, resulting in a woman experiencing difficulty achieving orgasm. Although the last days of the menstrual cycle are marked by a constant testosterone level, women's libido may boost as a result of the thickening of the uterine lining which stimulates nerve endings and makes a woman feel aroused. Also, during these days, estrogen levels also decline, resulting in a decrease of natural lubrication.

Although some specialists disagree with this theory, menopause is still considered by the majority a factor that can cause decreased sex desire in women. The levels of estrogen decrease at menopause and this usually causes a lower interest in sex and vaginal dryness which makes intercourse painful. However, the levels of testosterone increase at menopause and this may be why some women may experience a contrary effect of an increased libido.

Psychological and social factor
 lack of privacy or intimacy,
stress
fatigue,
distraction or depression. Environmental stress, such as prolonged exposure to elevated sound levels or bright light, can also affect libido.
 Other causes include experience of sexual abuse,
 assault, trauma, or neglect, body image issues and anxiety about engaging in sexual activity.

Physical factors

Physical factors that can affect libido include endocrine issues such as hypothyroidism, the effect of certain prescription medications (for example flutamide), and the attractiveness and biological fitness of one's partner, among various other lifestyle factors.

In males, the frequency of ejaculations affects the levels of sr testosterone, a hormone which promotes libido.
A study of 28 males aged 21–45 found that all but one of them had a peak (145.7% of baseline [117.8%-197.3%]) in serum testosterone on the 7th day of abstinence from ejaculation.

Anemia is a cause of lack of libido in women due to the loss of iron during the period.

Smoking, alcohol abuse, and the use of certain drugs can also lead to a decreased libido. Moreover, specialists suggest that several lifestyle changes such as  exercising, quitting smoking, lower consumption of alcohol or using prescription drugs may help increase one's sexual desires

Medications

Aphrodisiacs, such as dopaminergic psychostimulants, are a class of drugs which can increase libido. On the other hand, a reduced libido is also often iatrogenic and can be caused by many medications, such as hormonal contraception, SSRIs and other antidepressants, antipsychotics, opioids and beta blockers.

Testosterone is one of the hormones controlling libido in human beings. Emerging research is showing that hormonal contraception methods like Oral contraceptive pills (which rely on estrogen and progesterone together) are causing low libido in females by elevating levels of sex hormone binding globulin (SHBG). SHBG binds to sex hormones, including testosterone, rendering them unavailable. Research is showing that even after ending a hormonal contraceptive method, SHBG levels remain elevated and no reliable data exists to predict when this phenomenon will diminish.

Impact of age

Males reach the peak of their sex drive in their teens, while females reach it in their thirties. The surge in testosterone hits the male at puberty resulting in a sudden and extreme sex drive which reaches its peak at age 15-16, then drops slowly over his lifetime. In contrast, a female's libido increases slowly during adolescence and peaks in her mid-thirties. Actual testosterone and estrogen level affect a person's sex drive vary considerably.

Sexual desire disorders

There is no widely accepted measure of what is a healthy level for sex desire. Some people want to have sex every day, or more than once a day; others once a year or not at all. However, a person who lacks a desire for sexual activity for some period of time may be experiencing a hypoactive sexual desire disorder or may be asexual. A sexual desire disorder is more common in women than in men.
Erectile dysfunction can only occur in men and may be because of the lack of sexual desire, however, these two should not be confused. For example, large recreational doses of amphetamine or methamphetamine can simultaneously cause erectile dysfunction and significantly increase libido.
However, men can also experience a decrease in their libido as they age.

The American Medical Association has estimated that several million US women suffer from a female sexual arousal disorder, though arousal is not at all synonymous with desire, so this finding is of limited relevance to the discussion of libido. Some specialists claim that women may experience low libido due to some hormonal abnormalities such as lack of luteinising hormone or androgenic hormones, although these theories are still controversial. Also, women commonly lack sexual desire in the period immediately after giving birth. Moreover, any condition affecting the genital area can make women reject the idea of having intercourse. It has been estimated that half of women experience different health problems in the area of the vaginaand vulva, such as thinning, tightening, dryness or atrophy. Frustration may appear as a result of these issues and because many of them lead to painful sexual intercourse, many women prefer not having sex at all. Surgery or major health conditions such as arthritis, cancer, diabetes, high blood pressure, coronary artery disease or infertility may have the same effect in women.
Surgery that affects the hormonal levels in women include oophrectomies.