BIOCHEMISTRY PAPER 2 - 1ST MBBS KUHS SUPPLIMENTARY EXAMINATION - FEBRUARY 2015

Q.P.Code 106001                                            Reg. No.:…………………

First Professional MBBS Degree Supplementary Examinations - February 2015

BIOCHEMISTRY - PAPER  II

Time : 3 hrs                                                     Max marks : 50

                           

•      Answer all questions

•      Draw diagrams wherever necessary

Essay             (10)

1.    What is transcription. Enumerate the steps in transcription and add a note on post transcriptional modifications          (2+4+4=10)

Short essays           (2x5=10)

2.    How purine nucleotides are degraded. Add a note on abnormalities due to excessive purine catabolism.                                                                                                                    ( 3+2=5)

3.    Biochemical functions and deficiency manifestations of vitamin B₁₂                 (3+2=5)

Short notes (5x3=15)

4.    Detoxification by conjugation

5.    What are the salient features of genetic code

6.    Respiratory acidosis

7.    Name any two trace elements and mention the biological functions of each of them

8.    Functions of albumin

Answer briefly         (5x2=10)

9.    Salvage pathway of purine synthesis

10. Urea clearance test

11. Restriction enzymes

12. Acute intermittent porphyria

13. Principle of radioimmunoassay

Give precise answers        (5x1=5)

14. Folate trap

15. Define BMR

16. What is ceruloplasmin.

17. Oncogenes

18. What is the normal serum  level range of sodium and potassium