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Wednesday 20 February 2013

BIOCHEMISTRY PAPER 1-SUPPLI EXAM 2013-MBBS-KUHS


Q.P.Code:                                                        Reg. No.:………..

First Professional MBBS Degree Supplementary Examination, February  2013

BIOCHEMISTRY PAPER 1

Time: 3 HRS                                                                                                Total marks: 50


  • Answer all questions
  • Draw diagrams whenever necessary


Essay (10)

1. Describe by a flow diagram the reactions of glycolysis giving names of enzymes involved. Explain its regulation and add a note on the energetic in aerobic & anaerobic conditions. (6+2+2=10)

Short essays (2×5=10)

2. What are essential fatty acids? Enumerate them. List two functions and one deficiency manifestation.

3. Explain the digestion and absorption of carbohydrates

Short notes (5×3=15)

4. Alpha helix

5. Explain, why blood is collected in a fluoride tube for glucose estimation.

6. Glucose Alanine cycle

7. Enzymes as markers of myocardial infarction

8. Transamination

Answer briefly (5×2=10)

9. What is substrate level phosphorylation? Mention one example.

10. What are lipotropic factors? Name any two lipotropic agents

11. Four functions of cholesterol.

12. Why TCA cycle is called amphibolic.

13. Two co-enzymes roles of NADPH

Give precise answers (5×1=5)

14. One therapeutic use of enzyme

15. Compound that facilitates the release of O2 from oxyhaemoglobin

16. Lipoprotein involved in reverse cholesterol synthesis

17. Enzyme deficiency in Mc Ardle syndrome

18. Enzyme defect in lactose intolerance