PHARMACOLOGY PAPER-2-MODEL QUESTION-2ND YEAR MBBS-KUHS 2012-2013





Qp code:                                                  Reg Number:..............



Second Professional MBBS Degree Examination



(MODEL QUESTION PAPER)



PHARMACOLOGY- Paper II



Time: 2 hrs                       Max marks: 40



Answer all questions.

• Draw diagrams wherever necessary

Essay: (2x6=12)

1. Read the case history and answer the following questions: Ramesh 40 years, is an

alcoholic and a smoker. He gives history of nausea, abdominal pain, heart burn, loss

of appetite and one episode of haematemesis. Endoscopy confirms peptic ulceration

• Prescribe a drug for the above condition with dosage schedule

• Mention its mechanism of action and adverse effects

• What advice on life style modification should be given to him.

• List two drugs from different groups which can cause peptic ulceration

(2+2+ 1+1= 6)

2. Classify oral hypoglycemic drugs. Mention the mechanism of action, adverse effects

and drug interactions of any one drug. Name two drugs which cause hyperglycemia

(2 +1+1+1+1= 6)

Short notes: (5x3=15)

3. Protease inhibitors

4. Cyclophosphamide

5. OCP

6. Newer insulins

7. Fluconazole

Answer briefly (5x1=5)

8. Mention tow important uses and two adverse effects of methotrexate

9. Comment on the interaction produced by ciprofloxacin and theophylline

10. Specify the important spectrum of ceftriaxone

11. Pharmacological basis ofr combining anti tuberculous drugs

12. Mechanism of action of linezoilid

Name two drugs for (8x1=8)

13. Constipation

14. Penicillins effective against pseudomonas infection

15. MRSA infection

16. Superficial fungal infection

17. Lepromatous leprosy

18. Hypoglycaemic coma

19. Typhoid fever

20. Pseudomembranous colitis